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27 August 2017
Adel Hamed Elbaih1, Eman Adel Elzeky1, Islam Elshaboury1, Mohamed Oraby2 1) Department of Emergency Medicine, Faculty of Medicine, Suez Canal University, Ismailia, Egypt. 2) Department of
10 May 2017
Naoual Benhmidou1, Fadoua Rais1, Fadila
10 May 2017
Khadija Bellahammou1, Asmaa Lakhdissi1,
10 May 2017
Khaled Moursy Salama1, Monira T.

SMALL-CELL NEUROENDOCRINE CARCINOMA OF NASOPHARYNX: A CASE REPORT

Featured SMALL-CELL NEUROENDOCRINE CARCINOMA OF NASOPHARYNX: A CASE REPORT

Khadija Bellahammou1, Asmaa Lakhdissi1, Othman Akkar1, Fadila Kouhen2, Fadoua Rais2, Souhail Dahraoui3, Hind M'rabti1, Hassan Errihani1

1) Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco.

2) Department of Radiotherapy, National Institute of Oncology, Rabat, Morocco.

3) Department of Biology, Military Hospital Mohamed V, Rabat, Morocco.

Disclosure: The author has declared no conflicts of interest.

Received: 30.05.16 Accepted: 16.07.16

Citation: 10.5455/ijsm.nasopharynx-carcinoma

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Abstract:

Extra pulmonary small cell carcinomas are extremely rare, accounting for 0.1-0.4% of all malignancies and 2.5-4% of small cell carcinomas. In the head and neck region, the most common primary sites are the larynx, salivary gland, nasal cavity, paranasal sinus, tonsil, and oral cavity. Small cell carcinomas occurring in nasopharynx are extremely rare, to our best knowledge, only four cases of primary nasopharyngeal small cell carcinoma has been described in English literature.
We report another case of nasopharyngeal small cell carcinoma arising in a 46-year-old woman. She accused, for five months, nasal blockage, right hypoacousia, exophthalmos and reduced visual acuity. Cerebral and facial magnetic resonance imaging showed an extensive mass of the nasopharynx with the invasion of sphenoidal body, the diagnosis of disseminated small cell carcinoma of nasopahrynx was established. The patient received three courses of systemic chemotherapy; unfortunately, she died after the third course. The prognosis of such entity is poor and is similar to that for patients with extensive small cell lung cancer.

Keywords: nasopharynx, small-cell carcinoma, prognosis


How to Cite this Article

Bellahammou, K. et al., 2017. SMALL-CELL NEUROENDOCRINE CARCINOMA OF NASOPHARYNX: A CASE REPORT. International Journal of Surgery and Medicine, 3(1), p.1. Available at: http://dx.doi.org/10.5455/ijsm.nasopharynx-carcinoma
 

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