AGGRESSIVE MULTIPLE MYELOMA IN A YOUNG ADULT: A CASE REPORT

1) Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco.

2) Department of Biology, Military Hospital, Mohamed V, Rabat, Morocco

3) Department of Radiotherapy, National Institute of Oncology, Mohammed V University in Rabat, Morocco.

Disclosure: The author has declared no conflicts of interest.

Received: 05.04.16 Accepted: 28.04.16

Citation: 10.5455/ijsm.multiplemyeloma

Fulltext PDF Download

Cite/Export: EndNote/RefWorks

Abstract:

Multiple Myeloma is a blood cancer type B characterized by clonal proliferation of malignant plasma cells, the median age at diagnosis is 70 years, cases among younger patients are rare, and less than 0, 3 % patients are younger than 30 years in most series.
We report a case of a 25-year-old women; she was suffering of a sacred pain radiating towards the left lower limb and fatigue for three months, a magnetic resonance imaging for dorso-lumbar spine showed an expansive process and multiple osteolytic lesions in 2nd, 3rd and 4th sacred vertebras. She underwent a laparotomy that revealed a heavy mass invading the sacrum and the rectum. The histological examination with immunocytochemistry analysis revealed a plasmocytoma and the diagnosis of symptomatic multiple myeloma stage III was established then she received 2 courses of chemotherapy.
Despite the rarity of multiple myeloma among young patients, this diagnosis should be evoked when clinical, biological and radiological signs are in favor. It appears that there is no difference between younger and elderly patients on the presentation of the disease, although a longer survival has been reported among young patients.

Keywords: multiple myeloma, young, aggressive