GK News 2 - шаблон joomla Видео

Banner1

Log in
Powered by Spearhead Software Labs Joomla Facebook Like Button

GASTROINTESTINAL METASTASES OF MALIGNANT SKIN MELANOMA – REPORT OF 2 CASES AND REVIEW OF LITERATURE

According to the database from the National Cancer Registry malignant skin melanoma is one of the most malignant skin tumors.

The prognosis of malignant skin melanoma is bad because of its high degree of aggressiveness and tendency to metastases. Metastases in the gastrointestinal tract are frequently found as 80% of the malignant skin melanoma metastases in the gastrointestinal tract affect the small intestines.
We present 2 cases of patients with metastases in the gastrointestinal tract from malignant skin melanoma, where radical surgical interventions on gastrointestinal metastases have been performed.
The presence of distant metastases is the most important prognostic indicator for the survival of the patients with diagnosed malignant melanoma. In both cases presented surgical treatment has been made - resection of the small intestines area affected by the tumor metastases with subsequent anastomosis, observing the principles of operative surgical oncology. The patients were monitored during a period of 6 months and 1.5 years and their quality of life has been good.

Laparoscopic-assisted treatment of small bowel intussusception due to metastases from malignant melanoma 

In cases of metastasеs from malignant skin melanoma in GIT surgical interventions must be made. This way the survival rate of the patients can be increased and their quality of life can be improved.

Sergey Dimitrov Iliev1, Paulina Trifonova Vladova1, Savelina Popovska2

1) Department of Coloproctological and Purulent-septic Surgery, Medical University, Pleven, Bulgaria

2) Department of Pathology, Medical University, Pleven, Bulgaria

Disclosure: The author has declared no conflicts of interest.

Received: 25.12.15 Accepted: 18.02.16

Citation: doi:10.5455/ijsm.melanoma

Article statistics / Download Pdf


References:

1. Valerianova Z. Distribution of the malignant skin melanoma – status, tendency, and prognosis. A collection of abstracts for malignant skin melanoma. Pravetz, Bulgaria, June 2014, page 2.

2. Chodurek E., Orchel A., Orchel J., Kurkiewicz S., Gawlik N., et al. Evaluation of melanogenesis in A-375 cells in the presence of DMSO and analysis of the pyrolytic profile of isolated melanin. Scientific world journal, 2012, vol. 2012, 7 pages.
3. Mantas D., Tsaparas P., Charalampoudis P., Gorgas H., Kouraklis G. Emergency surgery for metastatic melanoma. International journal of surgical oncology. 2014, vol. 2014, 4 pages.
4. McDermott V., Low V., Keogan M., Lawrence J., Paulson E. Malignant melanoma metastatic to the gastrointestinal tract, AJR:166, April 1996.
5. Ettahri H., Elomrani F., Elkabous M., Rimini M., Boutayeb S., Mrabti H., Errihani H. Duodenal and gallbladder metastasis of regressive melanoma: a case report and review of the literature. Journal of gastrointestinal oncology. 2015 Oct; 6(5). [Pubmed] [PMC Free Fulltext]
6. Silverman J., Hamlin J. Large melanoma metastases to the gastrointestinal tract. Gut. 1989 Dec; 30(12):1783-5. [DOI via Crossref] [Pubmed] [PMC Free Fulltext]
7. Blazej Z., Carlson A., Granese J., Ross J., Mihm M., Jr, Slominski A. Current concepts of metastasis in melanoma. Expert Rev Dermatol. 2008 Oct; 3(5):569-585. [DOI via Crossref] [Pubmed] [PMC Free Fulltext]
8. Sourani N., Trojan A., Raab H., Antolovic D. Gastric metastasis of malignant melanoma: report of a case and review of available literature.Viszeralmedizin. 2014 Aug; 30(4):273-5. [Pubmed] [PMC Free Fulltext]
9. Goral V., Ucmak F., Yildirim S., Barutcu S., Ýleri S., Aslan Ý et al. Malignant melanoma of the stomach presenting in a woman: a case report. Journal of medical case reports. 2011 Mar 9;5:94. [DOI via Crossref] [Pubmed] [PMC Free Fulltext]
10. Dickson P., Gershenwald J. Staging and prognosis of cutaneous melanoma. Surgical oncology clinics of North America. 2011 Jan; 20(1):1-17. [DOI via Crossref] [Pubmed] [PMC Free Fulltext]
11. Kawashima A., Fishman EK, Kuhlman JE, Schuchter LM. CT of malignant melanoma: patterns of small bowel and mesenteric involvement. Journal of computed assisted tomography. 1991 Jul-Aug; 15(4):570-4.

Last modified onSunday, 03 June 2018 21:04